What role does mast cell disorder play in Long COVID?

Current reporting on COVID-19 tends to focus heavily on two areas: serious cases, where patients require intensive care treatment, and the number of deaths. Now, we are gradually seeing an increasing number of people still suffering from the associated health problems of COVID-19, however mildly, many months after becoming infected. These long-term consequences of the coronavirus are often referred to as "Long COVID" or Post-COVID Syndrome. Here we summarize the current findings surrounding Long COVID and explore the involvement of mast cells in the case of infection as well as the implications for those with a histamine intolerance.